Dr. Han Siew Ping

Lecturer



School of Life and Physical Sciences

SiewPing.Han@psb-academy.edu.sg

Dr. Han Siew Ping is currently a Lecturer in the School of Life and Physical Sciences. She graduated with a Bachelor of Science (Hons) from the National University of Singapore and a Doctor of Philosophy from the University of Queensland, Australia. She has over 10 years of research experience in both local and international institutions, and in fields ranging from protein science to mechanobiology.

 

Educational Qualifications

  • Doctor of Philosophy, University of Queensland, Australia, 2010
  • Bachelor of Science (Hons), National Universiy of Singapore, 2004

Professional Experiences

  • Lecturer, PSB Academy, 2015 – present
  • Patent Scientist, Spruson & Ferguson, 2014 - 2015
  • Postdoctoral Fellow, Mechanobiology Institute, 2013 - 2014
  • Postdoctoral Research Officer, Institute for Molecular Bioscience, Australia, 2010 - 2013
  • Research Assistant, National University of Singapore, 2004 -2007

Publications

  • Effect of voluntary running on adult hippocampal neurogenesis in cholinergic lesioned mice.
    Ho NF, Han SP, Dawe GS.
    BMC Neurosci. 2009 Jun 5;10:57. doi: 10.1186/1471-2202-10-57.
  • Hydrogen sulphide in the hypothalamus causes an ATP-sensitive K+ channel-dependent decrease in blood pressure in freely moving rats.
    Dawe GS, Han SP, Bian JS, Moore PK.
    Neuroscience. 2008 Mar 3;152(1):169-77. doi: 10.1016/j.neuroscience.2007.12.008
  • Chronic high-dose haloperidol has qualitatively similar effects to risperidone and clozapine on immediate-early gene and tyrosine hydroxylase expression in the rat locus coeruleus but not medial prefrontal cortex.
    Verma V, Lim EP, Han SP, Nagarajah R, Dawe GS
  • Complex evolutionary relationships among four classes of modular RNA-binding splicing regulators in eukaryotes: the hnRNP, SR, ELAV-like and CELF proteins.
    Tang YH, Han SP, Kassahn KS, Skarshewski A, Rothnagel JA, Smith R
    J Mol Evol. 2012 Dec;75(5-6):214-28. doi: 10.1007/s00239-012-9533-0. Epub 2012 Nov 24.
  • The cytoskeleton and classical cadherin adhesions.
    Han SP, Yap AS.
    Subcell Biochem. 2012;60:111-35. doi: 10.1007/978-94-007-4186-7_6. Review.
  • A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens.
    Verma S, Han SP, Michael M, Gomez GA, Yang Z, Teasdale RD, Ratheesh A, Kovacs EM, Ali RG, Yap AS.
    Mol Biol Cell. 2012 Dec;23(23):4601-10. doi: 10.1091/mbc.E12-08-0574. Epub 2012 Oct 10.
  • An α-catenin déjà vu.
    Han SP, Yap AS.
    Nat Cell Biol. 2013 Mar;15(3):238-9. doi: 10.1038/ncb2700.
  • Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens.
    Han SP, Gambin Y, Gomez GA, Verma S, Giles N, Michael M, Wu SK, Guo Z, Johnston W, Sierecki E, Parton RG, Alexandrov K, Yap AS.
    J Biol Chem. 2014 Mar 14;289(11):7764-75. doi: 10.1074/jbc.M113.544478. Epub 2014 Jan 27.
  • RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin.
    Truffi M, Dubreuil V, Liang X, Vacaresse N, Nigon F, Han SP, Yap AS, Gomez GA, Sap J.
    J Cell Sci. 2014 Jun 1;127(Pt 11):2420-32. doi: 10.1242/jcs.134379. Epub 2014 Mar 20.
  • Coronin 1B Reorganizes the Architecture of F-Actin Networks for Contractility at Steady-State and Apoptotic Adherens Junctions.
    Michael M, Meiring JC, Acharya BR, Matthews DR, Verma S, Han SP, Hill MM, Parton RG, Gomez GA, Yap AS.
    Dev Cell. 2016 Apr 4;37(1):58-71. doi: 10.1016/j.devcel.2016.03.008.
  • Epithelial Monolayers Coalesce on a Viscoelastic Substrate through Redistribution of Vinculin.
    Zheng JY, Han SP, Chiu YJ, Yip AK, Boichat N, Zhu SW, Zhong J, Matsudaira P.
    Biophys J. 2017 Aug 24. pii: S0006-3495(17)30853-6. doi: 10.1016/j.bpj.2017.07.027.